US Says “Remdesivir” Shows Clear-Cut Effect in Treating Coronavirus

Covid-19 patients on the antiviral remdesivir recovered more than 30 per cent faster than those on a placebo, the results of a major clinical trial showed Wednesday as a top US scientist hailed the drug’s “clear-cut” benefit.

It represents the first time any medication has been shown to improve outcomes against the Covid-19 illness, which has claimed more than 200,000 lives globally and brought the world economy to a grinding halt.

Anthony Fauci, who oversaw the investigation, told reporters at the White House: “The data shows that remdesivir has a clear-cut, significant, positive effect in diminishing the time to recovery.”

He added that the trial was proof “that a drug can block this virus,” and compared the finding to the arrival of the first antiretrovirals that worked against HIV in the 1980s, albeit with modest success at first.

A statement by the National Institute of Allergy and Infectious Diseases that Fauci heads said that patients on the drug had a 31 per cent faster time to recovery than those on a placebo.

“Specifically, the median time to recovery was 11 days for patients treated with remdesivir compared with 15 days for those who received placebo,” it said.

The results also suggested that people who were on the drug were less likely to die, although the difference was not huge: The mortality rate was 8.0 per cent for the group receiving remdesivir versus 11.6 per cent for the placebo group.

The trial began on February 21 and involved 1,063 people across 68 locations in the US, Europe and Asia.

The first patient to be enrolled was an American who was repatriated after being quarantined on the Diamond Princess cruise ship and was treated at the University of Nebraska Medical Center.

Neither the patients nor their physicians were aware of which group they belonged to, in order to eliminate unconscious bias.

Peter Horby, an epidemiologist at the University of Oxford who was not involved in the study, said: “We need to see the full results, but if confirmed this would be a fantastic result and great news for the fight against Covid-19.”

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